HN Theater @HNTheaterMonth

⬐ aaron695

None

⬐ stefanwlb

Fake news

⬐ taylorius

Let me guess - travel restrictions, lockdowns and eye wateringly expensive new fangled "vaccines"?

⬐ nigrioid

We need to continue feeding the Hacker News population increasingly large micro-redpills.

⬐ peyton

It’s mostly low-level IT people with no domain expertise.

⬐ stewartmcgown

Why the "vaccines" in quotes?

⬐ bandyaboot

None

⬐ Throwawayaerlei

Pretty sure you can figure out why, but if you deny this line of vaccines that are the oldest in existence from variolae vaccinae, Jenner's Latin for "smallpox of the cow," you deny everything called a vaccine.

Given that the only new wrinkle on Orthopox vaccines is taking the old derived from cowpox virus and preventing it from reproducing which is not a new or likely to be difficult technique including in manufacturing, there's effectively nothing "new fangled" about them.

Nor should there be anything "eye wateringly expensive" about them except Bavarian Nordic's JYNNEOS perhaps having a monopoly on this new type for now (they do in the US, don't know about Europe). For the older type vaccine the US started making it again after 9/11 so reclimbing the learning curve was done long ago, there's 100 million doses in our stockpile.

⬐ tinus_hn

Considering the very low spread of this disease, the low case fatality rate of the disease and the well-known risks of the vaccine, it’s probably an even worse idea to start a general vaccination campaign for this epidemic than the endless boosters for the COVID-19 vaccines.

⬐ Throwawayaerlei

That's obviously not on the US agenda, we're not getting huge numbers of doses of either kind manufactured. We are getting more JYNNEOS doses, and distributing doses of I assume it, and again with the assumptions so it can be used in the normal method of ring fencing known cases.

"Endless boosters for the COVID-19 vaccines" is a blatant lie, there's no more than for many previous types of vaccines, a total of two for those with good immune systems. Look up the US at the CDC or archived at the WHO vaccine schedules for all countries if you doubt.

But we shouldn't treat this latest zoonotic jump to humans casually, the more people who get it, the more chances it has to adapt better to humans and perhaps become more lethal as the Alpha and then Delta variants of classic Wuhan became. We know from the worst and most common form of smallpox that Orthopoxes have the potential of a 30% Case Fatality Rate (CFR).

⬐ tinus_hn

Fantasize away. The reality is that the boosters only work for 3 months so you just can’t make do with two if you want their amazing benefits, and you don’t get a QR code if you don’t get your mandatory umpteenth booster just because you have a good immune system.

And monkeypox is obviously not smallpox, it’s a variant that has approximately a 1% case fatality rate, in any case definitely nowhere near 30%.

And being careful is fine but any disease on the planet has a chance of becoming dangerous, it’s a part of life. We can’t keep panicking and lockdowning for that. And be sure to realize we had no problem with monkeypox mutating around in humans when it was far away in Africa.

⬐ Throwawayaerlei

"The reality is that the boosters only work for 3 months"

Nope, they make lasting, as far as we know permanent changes to your immune system as almost all vaccines do (TDaP to bacterial toxins an obvious exception).

You may be talking about how exposure to antigens creates an antibody fleet that wanes after a while, but only the insane recommend we try to maintain that vs. depend on memory B cells for antibodies and the equivalents for the other half of the adaptive immune system, the cellular one, for exposure later. We've never tried this tactic for a disease, although this is the first big, new one in the era of modern medicine (very possible the late 19th Century "Russian Flu" was caused by a now endemic "common cold" coronavirus, but nothing big since then until SARS, MERS and then COVID).

"and you don’t get a QR code if you don’t get your mandatory umpteenth booster just because you have a good immune system."

Where on earth do you live? Because this isn't what's happening anywhere in the US as far as I know, and I think I would have heard about localities trying to pull such stunts, especially after the cresting of the first wave of Omicron made all of this moot for the foreseeable future. If you're not here, then what I was talking about the FDA's authorizations and approvals for boost doses obviously wouldn't apply unless your country simply defers to them.

The rest shows you're simply not reading what I wrote, are unable to think about this monkeypox outbreak with its now primary human to human instead of rodent to human transmission mode (for the Western clade; not sure about the respective prevalence of transmission modes for the 10% lethal other clade) and apply lessons recently emphasized by our experience with COVID.

⬐ tinus_hn

So you have a narrow view of reality, think the US is the world and sling petty insults from behind your throwaway account. Such a tough guy.

⬐ forgotmypw17

I'm amazed that anyone believes anything coming from any large-scale official source anymore, given their webs of agendas and after the numerous lies in the past.

⬐ ryall

That generally prevents epidemics, yes.

⬐ mildmotive

Monkeypox vaccine pass when?