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THE GENE (An Intimate History)

Siddhartha Mukherjee · 4 HN comments
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Amazon Summary
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies —a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” ( Elle). "Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself." –Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost ” ( The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” ( The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” ( Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “ The Gene is a book we all should read” ( USA TODAY).
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I highly recommend "The Gene" by Siddhartha Mukherjee https://www.amazon.com/Gene-Intimate-History-Siddhartha-Mukh...
If you have some time, The Gene [0] is a good read. One of the cases the author describes is when a lot of people decided to be very optimistic at the same time and things didn't end well.

Not questioning your frustration though, but it's good to have extremely cautious people around.

[0]: https://www.amazon.com/Gene-Intimate-History-Siddhartha-Mukh...

In line with this, I'd also like to recommend 'The Gene'[0]. The author has informed me of new things (Even though I studied biochemistry during college) and also focused a lot on the ethical discussions relating to genetic modification. It also directly discusses CRISPR as it is quite new. I'd recommend all of Mukherjee's other books as well (Mainly Emperor of all Maladies).

[0]https://www.amazon.com/dp/1476733503

fossuser
I'd second this recommendation - currently reading it right now and it has the nice combination of being really interesting and really easy to read. Mukherjee's style is really clear and enjoyable.
If you are interested in learning more about CRISPR checkout this article - http://gizmodo.com/everything-you-need-to-know-about-crispr-... .

This podcast by Radiolab also breaks down the idea really well - http://www.radiolab.org/story/antibodies-part-1-crispr/ .

I am currently reading this book - The Gene http://www.amazon.com/Gene-Intimate-History-Siddhartha-Mukhe... to gain a better understanding of what genes are and I have found it to be really well written even for someone who last studied biology over 15 years ago.

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